Anti-THSD7A antibody (STJA0009722)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human THSD7A
General Information
| Short Description | Rabbit polyclonal anti-Thrombospondin type-1 domain-containing protein 7A for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | THSD7A |
| Gene ID | 221981 |
| Uniprot ID | THS7A_HUMAN |
| Immunogen | Synthesized peptide derived from human THSD7A |
| Specificity | This antibody detects endogenous levels of THSD7A at Human, Mouse |
Additional Info
| Post Translational Modifications | Proteolytic cleavage in the extracellular region generates a 210 kDa soluble form. Extensively N-glycosylated. |
| Function | Thrombospondin type-1 domain-containing protein 7A: Plays a role in actin cytoskeleton rearrangement. Thrombospondin type-1 domain-containing protein 7A, soluble form: The soluble form promotes endothelial cell migration and filopodia formation during sprouting angiogenesis via a FAK-dependent mechanism. |
| Protein Name | Thrombospondin Type-1 Domain-Containing Protein 7a Cleaved Into - Thrombospondin Type-1 Domain-Containing Protein 7a - Soluble Form |
| Database Links | Reactome: R-HSA-5083635Reactome: R-HSA-5173214 |
| Cellular Localisation | Thrombospondin Type-1 Domain-Containing Protein 7a: Cell MembraneSingle-Pass Type I Membrane ProteinCell ProjectionDetected On Podocyte Foot ProcessesThrombospondin Type-1 Domain-Containing Protein 7aSoluble Form: SecretedProteolytic Cleavage In The Extracellular Region Generates A 210 Kda Soluble Form |
| Alternative Antibody Names | Anti-Thrombospondin Type-1 Domain-Containing Protein 7a Cleaved Into - Thrombospondin Type-1 Domain-Containing Protein 7a - Soluble Form antibodyAnti-THSD7A antibodyAnti-KIAA0960 antibody |
Information sourced from Uniprot.org