Anti-Themis antibody [R37-2V-5] (STJA0035499)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from Themis
General Information
| Short Description | Rabbit monoclonal anti-Themis for use in WB, ICC, IF, IP and FC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ICC/IF/IP/FC |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R37-2V-5 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000IF 1:50-1:200IP 1:50FC 1:50 |
| Formulation | Liquid in PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | THEMIS |
| Gene ID | 387357 |
| Uniprot ID | THMS1_HUMAN |
| Immunogen | A synthesized peptide derived from Themis |
Additional Info
| Post Translational Modifications | Phosphorylated on Tyr residues quickly after TCR stimulation. |
| Function | Plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. Required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. Regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk. |
| Protein Name | Protein ThemisThymocyte-Expressed Molecule Involved In Selection |
| Database Links | |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Protein Themis antibodyAnti-Thymocyte-Expressed Molecule Involved In Selection antibodyAnti-THEMIS antibodyAnti-C6orf190 antibodyAnti-C6orf207 antibody |
Information sourced from Uniprot.org