Host: | Goat |
Applications: | Pep-ELISA/WB |
Reactivity: | Human/Mouse/Dog/Cow/Pig |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Goat polyclonal antibody anti-TH1L (Internal) is suitable for use in ELISA and Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: | 0.5 mg/mL |
Dilution Range: | WB-0.5-2µg/mlELISA-antibody detection limit dilution 1:16000. |
Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: | NELFCD |
Gene ID: | 51497 |
Uniprot ID: | NELFD_HUMAN |
Immunogen Region: | Internal |
Accession Number: | NP_945327.1 |
Immunogen Sequence: | NKRVSINKDE |
Function | Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. (Microbial infection) The NELF complex is involved in HIV-1 latency possibly involving recruitment of PCF11 to paused RNA polymerase II. |
Protein Name | Negative Elongation Factor C/DNelf-C/DTh1-Like Protein |
Database Links | Reactome: R-HSA-112382Reactome: R-HSA-113418Reactome: R-HSA-167152Reactome: R-HSA-167158Reactome: R-HSA-167200Reactome: R-HSA-167238Reactome: R-HSA-167242Reactome: R-HSA-167243Reactome: R-HSA-167246Reactome: R-HSA-167287Reactome: R-HSA-167290Reactome: R-HSA-674695Reactome: R-HSA-6796648Reactome: R-HSA-75955 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Negative Elongation Factor C/D antibodyAnti-Nelf-C/D antibodyAnti-Th1-Like Protein antibodyAnti-NELFCD antibodyAnti-NELFD antibodyAnti-TH1 antibodyAnti-TH1L antibodyAnti-HSPC130 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance