• STJ71525 Immunofluorescence analysis of paraformaldehyde fixed A431 cells, permeabilized with 0. 15% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml) , showing cytoplasmic staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml).
  • STJ71525 Flow cytometric analysis of paraformaldehyde fixed A431 cells (blue line) , permeabilized with 0. 5% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (1ug/ml). IgG control: Unimmunized goat IgG (black line) followed by Alexa Fluor 488 secondary antibody.

Anti-TGFBR3 antibody (Internal) (STJ71525)

SKU:
STJ71525-100

£303.50
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Host: Goat
Applications: Pep-ELISA/IF/FC
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-TGFBR3 (Internal) is suitable for use in ELISA, Immunofluorescence and Flow Cytometry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: IF-Strong expression of the protein seen in the cytoplasm of A431 cells. 10µg/ml
FC-Flow cytometric analysis of A431 cells. 10ug/ml
ELISA-antibody detection limit dilution 1:32000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: TGFBR3
Gene ID: 7049
Uniprot ID: TGBR3_HUMAN
Immunogen Region: Internal
Accession Number: NP_003234.2; NP_001182613.1
Immunogen Sequence: TKSIRDDIPSTQGN
Function Binds to TGF-beta. Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors. In gonadotrope cells, acts as an inhibin A coreceptor and regulates follicle-stimulating hormone (FSH) levels and female fertility.
Protein Name Transforming Growth Factor Beta Receptor Type 3
Tgf-Beta Receptor Type 3
Tgfr-3
Betaglycan
Transforming Growth Factor Beta Receptor Iii
Tgf-Beta Receptor Type Iii
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Secreted
Extracellular Space
Extracellular Matrix
Exists Both As A Membrane-Bound Form And As Soluble Form In Serum And In The Extracellular Matrix
Alternative Antibody Names Anti-Transforming Growth Factor Beta Receptor Type 3 antibody
Anti-Tgf-Beta Receptor Type 3 antibody
Anti-Tgfr-3 antibody
Anti-Betaglycan antibody
Anti-Transforming Growth Factor Beta Receptor Iii antibody
Anti-Tgf-Beta Receptor Type Iii antibody
Anti-TGFBR3 antibody

Information sourced from Uniprot.org

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