• Western blot analysis of extracts of various cell lines, using TGFBR3 antibody (STJ111006) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-TGFBR3 antibody (140-340) (STJ111006)

SKU:
STJ111006

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-TGFBR3 (140-340) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TGFBR3
Gene ID: 7049
Uniprot ID: TGBR3_HUMAN
Immunogen Region: 140-340
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 140-340 of human TGFBR3 (NP_003234.2).
Immunogen Sequence: ANFSLTAETEERNFPHGNEH LLNWARKEYGAVTSFTELKI ARNIYIKVGEDQVFPPKCNI GKNFLSLNYLAEYLQPKAAE GCVMSSQPQNEEVHIIELIT PNSNPYSAFQVDITIDIRPS QEDLEVVKNLILILKCKKSV NWVIKSFDVKGSLKIIAPNS IGFGKESERSMTMTKSIRDD IPSTQGNLVKWALDNGYSPI T
Post Translational Modifications Extensively modified by glycosaminoglycan groups (GAG).
Function Binds to TGF-beta. Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors. In gonadotrope cells, acts as an inhibin A coreceptor and regulates follicle-stimulating hormone (FSH) levels and female fertility.
Protein Name Transforming Growth Factor Beta Receptor Type 3
Tgf-Beta Receptor Type 3
Tgfr-3
Betaglycan
Transforming Growth Factor Beta Receptor Iii
Tgf-Beta Receptor Type Iii
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Secreted
Extracellular Space
Extracellular Matrix
Exists Both As A Membrane-Bound Form And As Soluble Form In Serum And In The Extracellular Matrix
Alternative Antibody Names Anti-Transforming Growth Factor Beta Receptor Type 3 antibody
Anti-Tgf-Beta Receptor Type 3 antibody
Anti-Tgfr-3 antibody
Anti-Betaglycan antibody
Anti-Transforming Growth Factor Beta Receptor Iii antibody
Anti-Tgf-Beta Receptor Type Iii antibody
Anti-TGFBR3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance