Post Translational Modifications | O-glycosylated. |
Function | Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma. |
Protein Name | Tissue Factor Pathway InhibitorTfpiExtrinsic Pathway InhibitorEpiLipoprotein-Associated Coagulation InhibitorLaci |
Database Links | Reactome: R-HSA-140834 |
Cellular Localisation | Isoform Alpha: SecretedIsoform Beta: Microsome MembraneLipid-AnchorGpi-Anchor |
Alternative Antibody Names | Anti-Tissue Factor Pathway Inhibitor antibodyAnti-Tfpi antibodyAnti-Extrinsic Pathway Inhibitor antibodyAnti-Epi antibodyAnti-Lipoprotein-Associated Coagulation Inhibitor antibodyAnti-Laci antibodyAnti-TFPI antibodyAnti-LACI antibodyAnti-TFPI1 antibody |
Information sourced from Uniprot.org