| Short Description : | Rabbit polyclonal TEX101 (44-150) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC-P/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TEX101 |
| Gene ID: | 83639 |
| Uniprot ID: | TX101_HUMAN |
| Immunogen Region: | 44-150 |
| Immunogen Sequence: | LYCQKGLSMTVEADPANMFN WTTEEVETCDKGALCQETIL IIKAGTETAILATKGCIPEG EEAITIVQHSSPPGLIVTSY SNYCEDSFCNDKDSLSQFWE FSETTAS |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 44-150 of human TEX101 (NP_113639.4). |
| Tissue Specificity | Detected in testis and spermatogonia. Not detected in spermatocytes. Detected in blood leukocytes. |
| Post Translational Modifications | N-glycosylated.by high mannose and/or biantennary complex and/or certain types of hybrid oligosaccharides.possesses different oligosaccharides chains according to its subcellular localization in the testis. Sheds from membrane raft by ACE and released from the cell surface of epididymal sperm while it passes through the caput epididymis leading to disappearance of TEX101 on spermatozoa.is essential to produce fertile spermatozoa. |
| Function | Plays a role in fertilization by controlling binding of sperm to zona pellucida and migration of spermatozoa into the oviduct. May play a role in signal transduction and promote protein tyrosine phosphorylation. |
| Protein Name | Testis-Expressed Protein 101Cell Surface Receptor Nyd-Sp8Scleroderma-Associated AutoantigenSpermatogenesis-Related Gene Protein |
| Database Links | Reactome: R-HSA-163125 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-AnchorMembrane RaftCytoplasmic VesicleSecretory VesicleAcrosomeSecretedLocated On Plasma Membrane Of SpermatocytesRound And Elongated SpermatidsAnd Testicular Spermatozoa |
| Alternative Antibody Names | Anti-Testis-Expressed Protein 101 antibodyAnti-Cell Surface Receptor Nyd-Sp8 antibodyAnti-Scleroderma-Associated Autoantigen antibodyAnti-Spermatogenesis-Related Gene Protein antibodyAnti-TEX101 antibodyAnti-SGRG antibodyAnti-UNQ867 antibodyAnti-PRO1884 antibody |
Information sourced from Uniprot.org
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