Anti-Terminal Deoxynucleotidyl Transferase antibody [SEN28] (STJ16101794)

SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
ImmunogenProkaryotic recombinant protein corresponding to the amino terminal region of the terminal deoxynucleotidyl transferase molecule.
STJ16101794-1
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General Information

Short DescriptionMouse monoclonal anti-Terminal Deoxynucleotidyl Transferase for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsIHC-P
HostMouse
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDSEN28
IsotypeIgG2a
ConjugationUnconjugated
Concentration>=30 mg/L
Dilution RangeIHC-P 1:100
FormulationTissue culture supernatant with sodium azide
Storage InstructionStore at 2-8°C for up to 1-year, upon receipt.

Target Information

ImmunogenProkaryotic recombinant protein corresponding to the amino terminal region of the terminal deoxynucleotidyl transferase molecule.

Additional Info

Background Terminal deoxynucleotidyl transferase (TdT) is a DNA polymerase of 58 kD located in the cell nucleus which catalyzes the polymerization of deoxynucleotides at the 3 hydroxyl ends of oligo or polydeoxynucleotide initiators and functions without a template. TdT is reported to be expressed in primitive T and B lymphocytes of the normal thymus and bone marrow. The identification of TdT-positive cell populations in primary and secondary lymphoid organs during maturation of the immune system is one area of interest but it is the reported occurrence of high levels of enzyme activity in white blood cells and bone marrow in certain leukemias which is of particular interest.

Information sourced from Uniprot.org

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