Anti-TECR antibody (259-308 aa) (STJ93407)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human GPSN2 at the amino acid range 259-308
General Information
| Short Description | Rabbit polyclonal anti-Very-long-chain enoyl-CoA reductase (259-308 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TECR |
| Gene ID | 9524 |
| Uniprot ID | TECR_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human GPSN2 at the amino acid range 259-308 |
| Immunogen Region | 259-308 aa |
| Specificity | GPSN2 Polyclonal Antibody detects endogenous levels of GPSN2 protein. |
Additional Info
| Post Translational Modifications | Glycosylated. |
| Function | Involved in both the production of very long-chain fatty acids for sphingolipid synthesis and the degradation of the sphingosine moiety in sphingolipids through the sphingosine 1-phosphate metabolic pathway. Catalyzes the last of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme reduces the trans-2,3-enoyl-CoA fatty acid intermediate to an acyl-CoA that can be further elongated by entering a new cycle of elongation. Thereby, it participates in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Catalyzes the saturation step of the sphingosine 1-phosphate metabolic pathway, the conversion of trans-2-hexadecenoyl-CoA to palmitoyl-CoA. |
| Protein Name | Very-Long-Chain Enoyl-Coa ReductaseSynaptic Glycoprotein Sc2Trans-2 -3-Enoyl-Coa ReductaseTer |
| Database Links | Reactome: R-HSA-75876 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Very-Long-Chain Enoyl-Coa Reductase antibodyAnti-Synaptic Glycoprotein Sc2 antibodyAnti-Trans-2 -3-Enoyl-Coa Reductase antibodyAnti-Ter antibodyAnti-TECR antibodyAnti-GPSN2 antibodyAnti-SC2 antibody |
Information sourced from Uniprot.org