Anti-TEAD3 antibody (211-260 aa) (STJ95963)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human TEAD3 at the amino acid range 211-260
General Information
| Short Description | Rabbit polyclonal anti-Transcriptional enhancer factor TEF-5 (211-260 aa) for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:10000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TEAD3 |
| Gene ID | 7005 |
| Uniprot ID | TEAD3_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human TEAD3 at the amino acid range 211-260 |
| Immunogen Region | 211-260 aa |
| Specificity | TEF-5 Polyclonal Antibody detects endogenous levels of TEF-5 protein. |
Additional Info
| Function | Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to multiple functional elements of the human chorionic somatomammotropin-B gene enhancer. |
| Protein Name | Transcriptional Enhancer Factor Tef-5Dtef-1Tea Domain Family Member 3Tead-3 |
| Database Links | Reactome: R-HSA-2032785Reactome: R-HSA-8951671 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcriptional Enhancer Factor Tef-5 antibodyAnti-Dtef-1 antibodyAnti-Tea Domain Family Member 3 antibodyAnti-Tead-3 antibodyAnti-TEAD3 antibodyAnti-TEAD5 antibodyAnti-TEF5 antibody |
Information sourced from Uniprot.org