| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TCEA1 |
| Gene ID: | 6917 |
| Uniprot ID: | TCEA1_HUMAN |
| Immunogen Region: | 75-140 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 75-140 of human TCEA1 (NP_006747.1). |
| Immunogen Sequence: | KLLDGPSTEKDLDEKKKEPA ITSQNSPEAREESTSSGNVS NRKDETNARDTYVSSFPRAP STSDSV |
| Function | Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus. |
| Protein Name | Transcription Elongation Factor A Protein 1Transcription Elongation Factor S-Ii Protein 1Transcription Elongation Factor Tfiis.o |
| Database Links | Reactome: R-HSA-112382Reactome: R-HSA-167152Reactome: R-HSA-167200Reactome: R-HSA-167238Reactome: R-HSA-167243Reactome: R-HSA-167246Reactome: R-HSA-167287Reactome: R-HSA-167290Reactome: R-HSA-674695Reactome: R-HSA-6781823Reactome: R-HSA-6781827Reactome: R-HSA-6782135Reactome: R-HSA-6782210Reactome: R-HSA-6796648Reactome: R-HSA-75955 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcription Elongation Factor A Protein 1 antibodyAnti-Transcription Elongation Factor S-Ii Protein 1 antibodyAnti-Transcription Elongation Factor Tfiis.o antibodyAnti-TCEA1 antibodyAnti-GTF2S antibodyAnti-TFIIS antibody |
Information sourced from Uniprot.org