| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Transforming growth factor beta regulator 1 is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TBRG1 |
| Gene ID: | 84897 |
| Uniprot ID: | TBRG1_HUMAN |
| Specificity: | This antibody detects endogenous levels of TBRG1 at Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from human TBRG1 |
| Post Translational Modifications | Ubiquitinated.mediated by MDM2 and leading to its subsequent proteasomal degradation. |
| Function | Acts as a growth inhibitor. Can activate p53/TP53, causes G1 arrest and collaborates with CDKN2A to restrict proliferation, but does not require either protein to inhibit DNA synthesis. Redistributes CDKN2A into the nucleoplasm. Involved in maintaining chromosomal stability. |
| Protein Name | Transforming Growth Factor Beta Regulator 1Nuclear Interactor Of Arf And Mdm2 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transforming Growth Factor Beta Regulator 1 antibodyAnti-Nuclear Interactor Of Arf And Mdm2 antibodyAnti-TBRG1 antibodyAnti-NIAM antibody |
Information sourced from Uniprot.org