| Host: | Mouse |
| Applications: | WB/IF/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal anti-T-Box Brain Protein 1 (AA range: 1-682) for use in WB, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | PTR1395 |
| Conjugation: | Unconjugated |
| Formulation: | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification: | The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen. |
| Dilution Range: | WB 1:500-2000IF 1:100-500ELISA 1:1000-5000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TBR1 |
| Gene ID: | 10716 |
| Uniprot ID: | TBR1_HUMAN |
| Immunogen Region: | AA range: 1-682 |
| Specificity: | This antibody detects endogenous levels of TBR1 protein. |
| Immunogen: | AA range: 1-682 |
| Function | Transcriptional repressor involved in multiple aspects of cortical development, including neuronal migration, laminar and areal identity, and axonal projection. As transcriptional repressor of FEZF2, it blocks the formation of the corticospinal (CS) tract from layer 6 projection neurons, thereby restricting the origin of CS axons specifically to layer 5 neurons. |
| Protein Name | T-Box Brain Protein 1T-Brain-1Tbr-1Tes-56 |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-T-Box Brain Protein 1 antibodyAnti-T-Brain-1 antibodyAnti-Tbr-1 antibodyAnti-Tes-56 antibodyAnti-TBR1 antibody |
Information sourced from Uniprot.org
