| Short Description : | Rabbit monoclonal TBR1 (1-100) antibody for use in WB, IF, ICC and ELISA in mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S6MR |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TBR1 |
| Gene ID: | 10716 |
| Uniprot ID: | TBR1_HUMAN |
| Immunogen Region: | 1-100 |
| Immunogen Sequence: | MQLEHCLSPSIMLSKKFLNV SSSYPHSGGSELVLHDHPII STTDNLERSSPLKKITRGMT NQSDTDNFPDSKDSPGDVQR SKLSPVLDGVSELRHSFDGS |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TBR1 (Q16650). |
| Tissue Specificity | Brain. |
| Function | Transcriptional repressor involved in multiple aspects of cortical development, including neuronal migration, laminar and areal identity, and axonal projection. As transcriptional repressor of FEZF2, it blocks the formation of the corticospinal (CS) tract from layer 6 projection neurons, thereby restricting the origin of CS axons specifically to layer 5 neurons. |
| Protein Name | T-Box Brain Protein 1T-Brain-1Tbr-1Tes-56 |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-T-Box Brain Protein 1 antibodyAnti-T-Brain-1 antibodyAnti-Tbr-1 antibodyAnti-Tes-56 antibodyAnti-TBR1 antibody |
Information sourced from Uniprot.org
