• Western blot analysis of various lysates using TBL1X Rabbit polyclonal antibody (STJ117296) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.

Anti-TBL1X antibody (100-200) (STJ117296)

SKU:
STJ117296

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-TBL1X (100-200) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TBL1X
Gene ID: 6907
Uniprot ID: TBL1X_HUMAN
Immunogen Region: 100-200
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human TBL1X (NP_005638.1).
Immunogen Sequence: LISILQKGLQYVEAEISINE DGTVFDGRPIESLSLIDAVM PDVVQTRQQAFREKLAQQQA SAAAAAAAATAAATAATTTS AGVSHQNPSKNREATVNGEE N
Tissue Specificity Ubiquitous.
Function F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange.
Protein Name F-Box-Like/Wd Repeat-Containing Protein Tbl1x
Smap55
Transducin Beta-Like Protein 1x
Transducin-Beta-Like Protein 1 - X-Linked
Database Links Reactome: R-HSA-1368082
Reactome: R-HSA-1368108
Reactome: R-HSA-1989781
Reactome: R-HSA-2122947
Reactome: R-HSA-2151201
Reactome: R-HSA-2426168
Reactome: R-HSA-2644606
Reactome: R-HSA-2894862
Reactome: R-HSA-3214815
Reactome: R-HSA-350054
Reactome: R-HSA-381340
Reactome: R-HSA-400206
Reactome: R-HSA-400253
Reactome: R-HSA-9022537
Reactome: R-HSA-9022692
Reactome: R-HSA-9029569
Reactome: R-HSA-9609690
Reactome: R-HSA-9707564
Reactome: R-HSA-9707616
Cellular Localisation Nucleus
Colocalized With Mecp2 To The Heterochromatin Foci
Alternative Antibody Names Anti-F-Box-Like/Wd Repeat-Containing Protein Tbl1x antibody
Anti-Smap55 antibody
Anti-Transducin Beta-Like Protein 1x antibody
Anti-Transducin-Beta-Like Protein 1 - X-Linked antibody
Anti-TBL1X antibody
Anti-TBL1 antibody

Information sourced from Uniprot.org

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