| Short Description : | Rabbit polyclonal anti-TAS2R1 (200-300 aa) for use in IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IHC/WB |
| Host: | Rabbit |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB (confirmed by recombinant protein). A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. |
| Formulation: | Lyophilised |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | TAS2R1 |
| Gene ID: | 50834 |
| Uniprot ID: | TA2R1_HUMAN |
| Immunogen: | A synthetic peptide from aa region 200-300 of human TAS2R1 conjugated to an immunogenic carrier protein was used as the antigen. |
| Immunogen Region: | 200-300 aa |
| Specificity: | Specific for TAS2R1. |
| Function | Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. |
| Protein Name | Taste Receptor Type 2 Member 1T2r1Taste Receptor Family B Member 7Trb7 |
| Database Links | Reactome: R-HSA-418594Reactome: R-HSA-420499Reactome: R-HSA-9717207 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Taste Receptor Type 2 Member 1 antibodyAnti-T2r1 antibodyAnti-Taste Receptor Family B Member 7 antibodyAnti-Trb7 antibodyAnti-TAS2R1 antibody |
Information sourced from Uniprot.org
