| Short Description : | Rabbit polyclonal anti-T-cell-interacting, activating receptor on myeloid cells protein 1 (36-86 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TARM1 |
| Gene ID: | 441864 |
| Uniprot ID: | TARM1_HUMAN |
| Immunogen: | Synthesized peptide derived from the human TARM1 at the amino acid range 36-86 |
| Immunogen Region: | 36-86 aa |
| Specificity: | This antibody detects endogenous levels of TARM1 at Human/Mouse |
| Post Translational Modifications | N-glycosylated. |
| Function | May act as receptor. Negatively regulates TCR-mediated CD4(+) T cell proliferation and activation, possibly by binding an unknown ligand on the T cell surface. Enhances Toll-like receptor-mediated production of pro-inflammatory cytokines by macrophages and neutrophils. |
| Protein Name | T-Cell-Interacting - Activating Receptor On Myeloid Cells Protein 1Oscar-Like Transcript-2 ProteinOlt-2 |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-T-Cell-Interacting - Activating Receptor On Myeloid Cells Protein 1 antibodyAnti-Oscar-Like Transcript-2 Protein antibodyAnti-Olt-2 antibodyAnti-TARM1 antibody |
Information sourced from Uniprot.org
