| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:5000IHC-P:1:50-1:100IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TAPBP |
| Gene ID: | 6892 |
| Uniprot ID: | TPSN_HUMAN |
| Immunogen Region: | 30-260 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-260 of human TAPBP (NP_757345.2). |
| Immunogen Sequence: | VEDASGKGLAKRPGALLLRQ GPGEPPPRPDLDPELYLSVH DPAGALQAAFRRYPRGAPAP HCEMSRFVPLPASAKWASGL TPAQNCPRALDGAWLMVSIS SPVLSLSSLLRPQPEPQQEP VLITMATVVLTVLTHTPAPR VRLGQDALLDLSFAYMPPTS EAASSLAPGPPPFGLEWRRQ HLGKGHLLLAATPGLNGQMP AAQEGAVAFAAWDDDEPWGP WTGNGTFWLPT |
| Tissue Specificity | Neutrophils, mostly in fully differentiated cells. |
| Function | Involved in the association of MHC class I with transporter associated with antigen processing (TAP) and in the assembly of MHC class I with peptide (peptide loading). |
| Protein Name | TapasinTpnTpsnNgs-17Tap-Associated ProteinTap-Binding Protein |
| Database Links | Reactome: R-HSA-1236974Reactome: R-HSA-983170 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Tapasin antibodyAnti-Tpn antibodyAnti-Tpsn antibodyAnti-Ngs-17 antibodyAnti-Tap-Associated Protein antibodyAnti-Tap-Binding Protein antibodyAnti-TAPBP antibodyAnti-NGS17 antibodyAnti-TAPA antibody |
Information sourced from Uniprot.org