| Post Translational Modifications | Under stimulation by forskolin, Isoform 1 is phosphorylated by protein kinase A (PKA). |
| Function | Cell type-specific subunit of the general transcription factor TFIID that may function as a gene-selective coactivator in certain cells. TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. TAF4B is a transcriptional coactivator of the p65/RELA NF-kappa-B subunit. Involved in the activation of a subset of antiapoptotic genes including TNFAIP3. May be involved in regulating folliculogenesis. Through interaction with OCBA/POU2AF1, acts as a coactivator of B-cell-specific transcription. Plays a role in spermiogenesis and oogenesis. |
| Protein Name | Transcription Initiation Factor Tfiid Subunit 4bTranscription Initiation Factor Tfiid 105 Kda SubunitTaf(Ii105Tafii-105Tafii105 |
| Database Links | Reactome: R-HSA-167161Reactome: R-HSA-167162Reactome: R-HSA-167172Reactome: R-HSA-674695Reactome: R-HSA-6804756Reactome: R-HSA-73776Reactome: R-HSA-73779Reactome: R-HSA-75953Reactome: R-HSA-76042 |
| Cellular Localisation | NucleusCytoplasmExport Into The Cytoplasm Is Mediated By A Crm1-Independent Nuclear Export Pathway And Not By Phosphorylation |
| Alternative Antibody Names | Anti-Transcription Initiation Factor Tfiid Subunit 4b antibodyAnti-Transcription Initiation Factor Tfiid 105 Kda Subunit antibodyAnti-Taf(Ii105 antibodyAnti-Tafii-105 antibodyAnti-Tafii105 antibodyAnti-TAF4B antibodyAnti-TAF2C2 antibodyAnti-TAFII105 antibody |
Information sourced from Uniprot.org
