| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Transcription initiation factor TFIID subunit 4B105 is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TAF4B |
| Gene ID: | 6875 |
| Uniprot ID: | TAF4B_HUMAN |
| Specificity: | TAF4B Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from part of the human protein |
| Post Translational Modifications | Under stimulation by forskolin, Isoform 1 is phosphorylated by protein kinase A (PKA). |
| Function | Cell type-specific subunit of the general transcription factor TFIID that may function as a gene-selective coactivator in certain cells. TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. TAF4B is a transcriptional coactivator of the p65/RELA NF-kappa-B subunit. Involved in the activation of a subset of antiapoptotic genes including TNFAIP3. May be involved in regulating folliculogenesis. Through interaction with OCBA/POU2AF1, acts as a coactivator of B-cell-specific transcription. Plays a role in spermiogenesis and oogenesis. |
| Protein Name | Transcription Initiation Factor Tfiid Subunit 4bTranscription Initiation Factor Tfiid 105 Kda SubunitTaf(Ii105Tafii-105Tafii105 |
| Database Links | Reactome: R-HSA-167161Reactome: R-HSA-167162Reactome: R-HSA-167172Reactome: R-HSA-674695Reactome: R-HSA-6804756Reactome: R-HSA-73776Reactome: R-HSA-73779Reactome: R-HSA-75953Reactome: R-HSA-76042 |
| Cellular Localisation | NucleusCytoplasmExport Into The Cytoplasm Is Mediated By A Crm1-Independent Nuclear Export Pathway And Not By Phosphorylation |
| Alternative Antibody Names | Anti-Transcription Initiation Factor Tfiid Subunit 4b antibodyAnti-Transcription Initiation Factor Tfiid 105 Kda Subunit antibodyAnti-Taf(Ii105 antibodyAnti-Tafii-105 antibodyAnti-Tafii105 antibodyAnti-TAF4B antibodyAnti-TAF2C2 antibodyAnti-TAFII105 antibody |
Information sourced from Uniprot.org
