| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Monoclonal |
| Clone ID: |
SRM |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
TAF1C |
| Gene ID: |
9013 |
| Uniprot ID: |
TAF1C_HUMAN |
| Immunogen Region: |
75-221 aa |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 75-221 of human TAF1C (NP_005670.4). |
| Immunogen Sequence: |
PWDPGLTARDLLFRGGCRYR KRPRVVLDVTEQISRFLLDH GDVAFAPLGKLMLENFKLEG AGSRTKKKTVVSVKKLLQDL GGHQPWGCPWAYLSNRQRRF SILGGPILGTSVASHLAELL HEELVLRWEQLLLDEACTGG ALAWVPG |
| Function | Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (pre-initiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. Recruits RNA polymerase I to the rRNA gene promoter via interaction with RRN3. |
| Protein Name | Tata Box-Binding Protein-Associated Factor Rna Polymerase I Subunit CRna Polymerase I-Specific Tbp-Associated Factor 110 KdaTafi110Tata Box-Binding Protein-Associated Factor 1cTbp-Associated Factor 1cTranscription Initiation Factor Sl1/Tif-Ib Subunit C |
| Database Links | Reactome: R-HSA-427359Reactome: R-HSA-427413Reactome: R-HSA-5250924Reactome: R-HSA-73762Reactome: R-HSA-73772Reactome: R-HSA-73863 |
| Cellular Localisation | NucleusNucleolus |
| Alternative Antibody Names | Anti-Tata Box-Binding Protein-Associated Factor Rna Polymerase I Subunit C antibodyAnti-Rna Polymerase I-Specific Tbp-Associated Factor 110 Kda antibodyAnti-Tafi110 antibodyAnti-Tata Box-Binding Protein-Associated Factor 1c antibodyAnti-Tbp-Associated Factor 1c antibodyAnti-Transcription Initiation Factor Sl1/Tif-Ib Subunit C antibodyAnti-TAF1C antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
