| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-TATA-binding protein-associated factor 2N68 (351-400 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:5000 IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TAF15 |
| Gene ID: | 8148 |
| Uniprot ID: | RBP56_HUMAN |
| Immunogen Region: | 351-400 aa |
| Specificity: | TAF II p68 Polyclonal Antibody detects endogenous levels of TAF II p68 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human TAF15 at the amino acid range 351-400 |
| Post Translational Modifications | Dimethylated by PRMT1 at Arg-206 to asymmetric dimethylarginine. The methylation may favor nuclear localization and positive regulation of TAF15 transcriptional activity. ADP-ribosylated during genotoxic stress. |
| Function | RNA and ssDNA-binding protein that may play specific roles during transcription initiation at distinct promoters. Can enter the preinitiation complex together with the RNA polymerase II (Pol II). |
| Protein Name | Tata-Binding Protein-Associated Factor 2n 68 Kda Tata-Binding Protein-Associated Factor Taf(Ii68 Tafii68 Rna-Binding Protein 56 |
| Database Links | Reactome: R-HSA-167161 Reactome: R-HSA-167162 Reactome: R-HSA-167172 Reactome: R-HSA-674695 Reactome: R-HSA-6804756 Reactome: R-HSA-73776 Reactome: R-HSA-73779 Reactome: R-HSA-75953 Reactome: R-HSA-76042 |
| Cellular Localisation | Nucleus Cytoplasm Shuttles From The Nucleus To The Cytoplasm |
| Alternative Antibody Names | Anti-Tata-Binding Protein-Associated Factor 2n antibody Anti-68 Kda Tata-Binding Protein-Associated Factor antibody Anti-Taf(Ii68 antibody Anti-Tafii68 antibody Anti-Rna-Binding Protein 56 antibody Anti-TAF15 antibody Anti-RBP56 antibody Anti-TAF2N antibody |
Information sourced from Uniprot.org