| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/IP/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200IP:0.5 Mu g-4 Mu g antibody for 200 Mu g-400 Mu g extracts of whole cellsELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specif |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TAF15 |
| Gene ID: | 8148 |
| Uniprot ID: | RBP56_HUMAN |
| Immunogen Region: | 1-280 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human TAF15 (NP_631961.1). |
| Immunogen Sequence: | MSDSGSYGQSGGEQQSYSTY GNPGSQGYGQASQSYSGYGQ TTDSSYGQNYSGYSSYGQSQ SGYSQSYGGYENQKQSSYSQ QPYNNQGQQQNMESSGSQGG RAPSYDQPDYGQQDSYDQQS GYDQHQGSYDEQSNYDQQHD SYSQNQQSYHSQRENYSHHT QDDRRDVSRYGEDNRGYGGS QGGGRGRGGYDKDGRGPMTG SSGGDRGGFKNFGGHRDYGP RTDADSESDNSDNNTIFVQ |
| Tissue Specificity | Ubiquitous. Observed in all fetal and adult tissues. |
| Post Translational Modifications | Dimethylated by PRMT1 at Arg-206 to asymmetric dimethylarginine. The methylation may favor nuclear localization and positive regulation of TAF15 transcriptional activity. ADP-ribosylated during genotoxic stress. |
| Function | RNA and ssDNA-binding protein that may play specific roles during transcription initiation at distinct promoters. Can enter the preinitiation complex together with the RNA polymerase II (Pol II). |
| Protein Name | Tata-Binding Protein-Associated Factor 2n68 Kda Tata-Binding Protein-Associated FactorTaf(Ii68Tafii68Rna-Binding Protein 56 |
| Database Links | Reactome: R-HSA-167161Reactome: R-HSA-167162Reactome: R-HSA-167172Reactome: R-HSA-674695Reactome: R-HSA-6804756Reactome: R-HSA-73776Reactome: R-HSA-73779Reactome: R-HSA-75953Reactome: R-HSA-76042 |
| Cellular Localisation | NucleusCytoplasmShuttles From The Nucleus To The Cytoplasm |
| Alternative Antibody Names | Anti-Tata-Binding Protein-Associated Factor 2n antibodyAnti-68 Kda Tata-Binding Protein-Associated Factor antibodyAnti-Taf(Ii68 antibodyAnti-Tafii68 antibodyAnti-Rna-Binding Protein 56 antibodyAnti-TAF15 antibodyAnti-RBP56 antibodyAnti-TAF2N antibody |
Information sourced from Uniprot.org