| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TADA3 |
| Gene ID: | 10474 |
| Uniprot ID: | TADA3_HUMAN |
| Immunogen Region: | 270-369 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 270-369 of human TADA3 (NP_597814.1). |
| Immunogen Sequence: | EENIISPMEDSPIPDMSGKE SGADGASTSPRNQNKPFSVP HTKSLESRIKEELIAQGLLE SEDRPAEDSEDEVLAELRKR QAELKALSAHNRTKKHDLLR |
| Tissue Specificity | Ubiquitously expressed. |
| Function | Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex. Also known as a coactivator for p53/TP53-dependent transcriptional activation. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. |
| Protein Name | Transcriptional Adapter 3Ada3 HomologHada3Staf54Transcriptional Adapter 3-LikeAda3-Like Protein |
| Database Links | Reactome: R-HSA-3214847Reactome: R-HSA-5689880Reactome: R-HSA-9772755 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcriptional Adapter 3 antibodyAnti-Ada3 Homolog antibodyAnti-Hada3 antibodyAnti-Staf54 antibodyAnti-Transcriptional Adapter 3-Like antibodyAnti-Ada3-Like Protein antibodyAnti-TADA3 antibodyAnti-ADA3 antibodyAnti-TADA3L antibody |
Information sourced from Uniprot.org
![Western blot analysis of lysates from wild type (WT) and TWF2 knockout (KO) 293T cells, using [KO Validated] TWF2 Rabbit polyclonal antibody (STJ11100774) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/89710/358192/STJ11100774_1__12392.1713122508.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and TWF2 knockout (KO) 293T cells, using [KO Validated] TWF2 Rabbit polyclonal antibody (STJ11100774) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.")
