| Host: | Rabbit |
| Applications: | WB/IF/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Neuromedin-K receptor (401-450) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IF 1:200-1:1000ELISA 1:10000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TACR3 |
| Gene ID: | 6870 |
| Uniprot ID: | NK3R_HUMAN |
| Immunogen Region: | 401-450 |
| Specificity: | NK-3R Polyclonal Antibody detects endogenous levels of NK-3R protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human NK3R. AA range:401-450 |
| Post Translational Modifications | The anchoring of this receptor to the plasma membrane is probably mediated by the palmitoylation of a cysteine residue. |
| Function | This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: neuromedin-K > substance K > substance P. |
| Protein Name | Neuromedin-K ReceptorNkrNk-3 ReceptorNk-3rNeurokinin B ReceptorTachykinin Receptor 3 |
| Database Links | Reactome: R-HSA-380095Reactome: R-HSA-416476 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Neuromedin-K Receptor antibodyAnti-Nkr antibodyAnti-Nk-3 Receptor antibodyAnti-Nk-3r antibodyAnti-Neurokinin B Receptor antibodyAnti-Tachykinin Receptor 3 antibodyAnti-TACR3 antibodyAnti-NK3R antibodyAnti-TAC3R antibody |
Information sourced from Uniprot.org