| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-TACR3 (356-465) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TACR3 |
| Gene ID: |
6870 |
| Uniprot ID: |
NK3R_HUMAN |
| Immunogen Region: |
356-465 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 356-465 of human TACR3 (NP_001050.1). |
| Immunogen Sequence: |
YCCLNKRFRAGFKRAFRWCP FIKVSSYDELELKTTRFHPN RQSSMYTVTRMESMTVVFDP NDADTTRSSRKKRATPRDPS FNGCSRRNSKSASATSSFIS SPYTSVDEYS |
| Post Translational Modifications | The anchoring of this receptor to the plasma membrane is probably mediated by the palmitoylation of a cysteine residue. |
| Function | This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: neuromedin-K > substance K > substance P. |
| Protein Name | Neuromedin-K ReceptorNkrNk-3 ReceptorNk-3rNeurokinin B ReceptorTachykinin Receptor 3 |
| Database Links | Reactome: R-HSA-380095Reactome: R-HSA-416476 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Neuromedin-K Receptor antibodyAnti-Nkr antibodyAnti-Nk-3 Receptor antibodyAnti-Nk-3r antibodyAnti-Neurokinin B Receptor antibodyAnti-Tachykinin Receptor 3 antibodyAnti-TACR3 antibodyAnti-NK3R antibodyAnti-TAC3R antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
