| Short Description : | Rabbit polyclonal anti-Substance-P receptor (211-260) for use in WB, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IF/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-1:2000IF 1:200-1:1000ELISA 1:5000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TACR1 |
| Gene ID: | 6869 |
| Uniprot ID: | NK1R_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human NK1R. AA range:211-260 |
| Immunogen Region: | 211-260 |
| Specificity: | NK-1R Polyclonal Antibody detects endogenous levels of NK-1R protein. |
| Function | This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K. |
| Protein Name | Substance-P ReceptorSprNk-1 ReceptorNk-1rTachykinin Receptor 1 |
| Database Links | Reactome: R-HSA-380095Reactome: R-HSA-416476Reactome: R-HSA-8856825Reactome: R-HSA-8856828 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Substance-P Receptor antibodyAnti-Spr antibodyAnti-Nk-1 Receptor antibodyAnti-Nk-1r antibodyAnti-Tachykinin Receptor 1 antibodyAnti-TACR1 antibodyAnti-NK1R antibodyAnti-TAC1R antibody |
Information sourced from Uniprot.org
