| Function | Olfactory receptor specific for trace amines, such as triethylamine, N,N-dimethylcyclohexylamine (DMCHA), beta-phenylethylamine (beta-PEA), cadaverine (CAD) and polyamines such as spermine and spermidine. Trace amine compounds are enriched in animal body fluids and act on trace amine-associated receptors (TAARs) to elicit both intraspecific and interspecific innate behaviors. Trace amine-binding causes a conformation change that triggers signaling via G(s)-class of G alpha proteins (GNAL or GNAS). In mature olfactory sensory neurons, Taar9 is coupled with GNAL/G(olf)G alpha protein and mediates activation of adenylate cyclase activity to activate cAMP signaling and eventually transmit odorant signals to achieve membrane depolarization. In immature olfactory sensory neurons, Taar9 is coupled with GNAS/G(s) G alpha proteins. |
| Protein Name | Trace Amine-Associated Receptor 9Tar-9Trace Amine Receptor 9Mtaar9 |
| Database Links | Reactome: R-MMU-375280Reactome: -MMU-418555 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Trace Amine-Associated Receptor 9 antibodyAnti-Tar-9 antibodyAnti-Trace Amine Receptor 9 antibodyAnti-Mtaar9 antibodyAnti-Taar9 antibody |
Information sourced from Uniprot.org
