| Host: | Rabbit |
| Applications: | IHC |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-TAAR5 (C-Term) is suitable for use in Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Lyophilised |
| Purification: | IgG purified |
| Dilution Range: | IHC. A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | Taar5 |
| Gene ID: | 215854 |
| Uniprot ID: | TAAR5_MOUSE |
| Immunogen Region: | C-Term |
| Specificity: | Specific for TAAR5. |
| Immunogen: | A synthetic peptide from c-terminal region of mouse trace amine-associated receptor 5 (TAAR5) conjugated to an immunogenic carrier protein was used as the antigen. |
| Function | Olfactory receptor specific for trimethylamine, a trace amine enriched in the urine of male mice, playing a role in social behavior. Also activated by N-methylpiperidine. Trimethylamine is present at high concentration in the urine of male mice after puberty and acts as an attractant. Trimethylamine-binding causes a conformation change that triggers signaling via G(s)-class of G alpha proteins (GNAL or GNAS). Also required to provide olfactory input into limbic brain areas to regulate emotional behaviors likely via modulation of the serotonin system. |
| Protein Name | Trace Amine-Associated Receptor 5Tar-5Trace Amine Receptor 5Mtaar5Trimethylamine Receptor |
| Database Links | Reactome: R-MMU-375280Reactome: -MMU-418555 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Trace Amine-Associated Receptor 5 antibodyAnti-Tar-5 antibodyAnti-Trace Amine Receptor 5 antibodyAnti-Mtaar5 antibodyAnti-Trimethylamine Receptor antibodyAnti-Taar5 antibodyAnti-Gm227 antibody |
Information sourced from Uniprot.org