Anti-T Cell Leukemia/Lymphoma Protein 1A antibody [R07-3O8] (STJA0036781)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human TCL1
General Information
| Short Description | Rabbit monoclonal anti-T Cell Leukemia/Lymphoma Protein 1A for use in WB, IHC-P, ICC, IF and FC in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ICC/IF/FC |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R07-3O8 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100IF 1:50-1:200FC 1:50-1:100 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | TCL1A |
| Gene ID | 8115 |
| Uniprot ID | TCL1A_HUMAN |
| Immunogen | A synthesized peptide derived from human TCL1 |
Additional Info
| Tissue Specificity | Restricted in the T-cell lineage to immature thymocytes and activated peripheral lymphocytes. Preferentially expressed early in T- and B-lymphocyte differentiation. |
| Function | Enhances the phosphorylation and activation of AKT1, AKT2 and AKT3. Promotes nuclear translocation of AKT1. Enhances cell proliferation, stabilizes mitochondrial membrane potential and promotes cell survival. |
| Protein Name | T-Cell Leukemia/Lymphoma Protein 1aOncogene Tcl-1Oncogene Tcl1Protein P14 Tcl1 |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusMicrosomeEndoplasmic ReticulumMicrosomal Fraction |
| Alternative Antibody Names | Anti-T-Cell Leukemia/Lymphoma Protein 1a antibodyAnti-Oncogene Tcl-1 antibodyAnti-Oncogene Tcl1 antibodyAnti-Protein P14 Tcl1 antibodyAnti-TCL1A antibodyAnti-TCL1 antibody |
Information sourced from Uniprot.org