Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Synaptotagmin-2 (40-120 aa) is suitable for use in Western Blot and ELISA research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000 ELISA 1:5000-20000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | SYT2 |
Gene ID: | 127833 |
Uniprot ID: | SYT2_HUMAN |
Immunogen Region: | 40-120 aa |
Specificity: | SYT2 Polyclonal Antibody detects endogenous levels of protein. |
Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 40-120 |
Post Translational Modifications | Phosphorylation at Thr-199 by WNK1, changes the calcium requirement for SYT2-binding to phospholipid membranes. |
Function | Exhibits calcium-dependent phospholipid and inositol polyphosphate binding properties. May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. Plays a role in dendrite formation by melanocytes. |
Protein Name | Synaptotagmin-2 Synaptotagmin Ii Sytii |
Database Links | Reactome: R-HSA-5250958 Reactome: R-HSA-6794361 Reactome: R-HSA-8856825 Reactome: R-HSA-8856828 |
Cellular Localisation | Cytoplasmic Vesicle Secretory Vesicle Synaptic Vesicle Membrane Single-Pass Membrane Protein Chromaffin Granule Membrane Cytoplasm |
Alternative Antibody Names | Anti-Synaptotagmin-2 antibody Anti-Synaptotagmin Ii antibody Anti-Sytii antibody Anti-SYT2 antibody |
Information sourced from Uniprot.org