| Host: | Mouse |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-SYT1 is suitable for use in Western Blot research applications. |
| Clonality : | Monoclonal |
| Clone ID : | SM5200 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% sodium azide, 100 Mu g/ml BSA and 50% glycerol. |
| Purification: | Affinity purification |
| Dilution Range: | WB (H, M, R) 1:500-1:1000 |
| Storage Instruction: | Store at-20C for up to one year, and avoid repeated freeze-thaw cycles. |
| Gene Symbol: | Syt1 |
| Gene ID: | 20979 |
| Uniprot ID: | SYT1_MOUSE |
| Immunogen: | Recombinant protein corresponding to Mouse SYT1 |
| Post Translational Modifications | Glycosylated. |
| Function | Calcium sensor that participates in triggering neurotransmitter release at the synapse. May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner.these are neurexins, syntaxin and AP2. Plays a role in dendrite formation by melanocytes. |
| Protein Name | Synaptotagmin-1Synaptotagmin ISytiP65 |
| Database Links | Reactome: R-MMU-181429Reactome: -MMU-181430Reactome: -MMU-210500Reactome: -MMU-212676Reactome: -MMU-264642Reactome: -MMU-8856825Reactome: -MMU-8856828Reactome: -MMU-888590 |
| Cellular Localisation | Cytoplasmic VesicleSecretory Vesicle MembraneSingle-Pass Membrane ProteinSecretory VesicleSynaptic Vesicle MembraneChromaffin Granule MembraneCytoplasm |
| Alternative Antibody Names | Anti-Synaptotagmin-1 antibodyAnti-Synaptotagmin I antibodyAnti-Syti antibodyAnti-P65 antibodyAnti-Syt1 antibody |
Information sourced from Uniprot.org
