| Host: | Mouse |
| Applications: | IHC/WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-Synaptophysin (200-313 aa) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Monoclonal |
| Clone ID : | ABT533 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1k |
| Formulation: | Liquid in PBS pH7.2, 0.03% Proclin 300, with stabilizing protein. |
| Purification: | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Dilution Range: | IHC-P 1:200-400WB 1:200-1000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SYP |
| Gene ID: | 6855 |
| Uniprot ID: | SYPH_HUMAN |
| Immunogen Region: | 200-313 aa |
| Specificity: | The antibody can specifically recognize human Synaptophysin protein. |
| Immunogen: | Synthesized peptide derived from the human Synaptophysin at the amino acid range 200-313 |
| Post Translational Modifications | Ubiquitinated.mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation. Phosphorylated by SRC. |
| Function | Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity. |
| Protein Name | SynaptophysinMajor Synaptic Vesicle Protein P38 |
| Database Links | Reactome: R-HSA-9662360 |
| Cellular Localisation | Cytoplasmic VesicleSecretory VesicleSynaptic Vesicle MembraneMulti-Pass Membrane ProteinSynapseSynaptosome |
| Alternative Antibody Names | Anti-Synaptophysin antibodyAnti-Major Synaptic Vesicle Protein P38 antibodyAnti-SYP antibody |
Information sourced from Uniprot.org