| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit monoclonal antibody anti-Syntrophin alpha 1 (1-100) is suitable for use in Western Blot research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
S7MR |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SNTA1 |
| Gene ID: |
6640 |
| Uniprot ID: |
SNTA1_HUMAN |
| Immunogen Region: |
1-100 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Syntrophin alpha 1 (Q13424). |
| Immunogen Sequence: |
MASGRRAPRTGLLELRAGAG SGAGGERWQRVLLSLAEDVL TVSPADGDPGPEPGAPREQE PAQLNGAAEPGAGPPQLPEA LLLQRRRVTVRKADAGGLGI |
| Tissue Specificity | High expression in skeletal muscle and heart. Low expression in brain, pancreas, liver, kidney and lung. Not detected in placenta. |
| Post Translational Modifications | Phosphorylated by CaM-kinase II. Phosphorylation may inhibit the interaction with DMD. |
| Function | Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the extracellular matrix via the dystrophin glycoprotein complex. Plays an important role in synapse formation and in the organization of UTRN and acetylcholine receptors at the neuromuscular synapse. Binds to phosphatidylinositol 4,5-bisphosphate. |
| Protein Name | Alpha-1-Syntrophin59 Kda Dystrophin-Associated Protein A1 Acidic Component 1Pro-Tgf-Alpha Cytoplasmic Domain-Interacting Protein 1Tacip1Syntrophin-1 |
| Cellular Localisation | Cell MembraneSarcolemmaPeripheral Membrane ProteinCytoplasmic SideCell JunctionCytoplasmCytoskeletonIn Skeletal MuscleIt Localizes At The Cytoplasmic Side Of The Sarcolemmal Membrane And At Neuromuscular Junctions |
| Alternative Antibody Names | Anti-Alpha-1-Syntrophin antibodyAnti-59 Kda Dystrophin-Associated Protein A1 Acidic Component 1 antibodyAnti-Pro-Tgf-Alpha Cytoplasmic Domain-Interacting Protein 1 antibodyAnti-Tacip1 antibodyAnti-Syntrophin-1 antibodyAnti-SNTA1 antibodyAnti-SNT1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
