| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SYNGR1 |
| Gene ID: | 9145 |
| Uniprot ID: | SNG1_HUMAN |
| Immunogen Region: | 1-191 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-191 of human SYNGR1 (NP_663783.1). |
| Immunogen Sequence: | MEGGAYGAGKAGGAFDPYTL VRQPHTILRVVSWLFSIVVF GSIVNEGYLNSASEGEEFCI YNRNPNACSYGVAVGVLAFL TCLLYLALDVYFPQISSVKD RKKAVLSDIGVSAFWAFLWF VGFCYLANQWQVSKPKDNPL NEGTDAARAAIAFSFFSIFT WSLTAALAVRRFKDLSFQEE YSTLFPASAQP |
| Function | May play a role in regulated exocytosis. Modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in synaptic-like microvesicle formation and/or maturation. Involved in the regulation of short-term and long-term synaptic plasticity. |
| Protein Name | Synaptogyrin-1 |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | Cytoplasmic VesicleSecretory VesicleSynaptic Vesicle MembraneMulti-Pass Membrane ProteinMelanosomeIdentified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv |
| Alternative Antibody Names | Anti-Synaptogyrin-1 antibodyAnti-SYNGR1 antibody |
Information sourced from Uniprot.org
![Western blot analysis of lysates from wild type (WT) and PDCD6 knockout (KO) 293T cells, using [KO Validated] PDCD6 Rabbit polyclonal antibody (STJ11100800) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/89736/358213/STJ11100800_1__35533.1713122537.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and PDCD6 knockout (KO) 293T cells, using [KO Validated] PDCD6 Rabbit polyclonal antibody (STJ11100800) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")
