Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human/Rat/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit polyclonal antibody anti-Ras/Rap GTPase-activating protein SynGAP is suitable for use in Western Blot and ELISA research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | SYNGAP1 |
Gene ID: | 8831 |
Uniprot ID: | SYGP1_HUMAN |
Specificity: | SYGP1 Polyclonal Antibody detects endogenous levels of protein. |
Immunogen: | Synthesized peptide derived from part of the human protein |
Function | Major constituent of the PSD essential for postsynaptic signaling. Inhibitory regulator of the Ras-cAMP pathway. Member of the NMDAR signaling complex in excitatory synapses, it may play a role in NMDAR-dependent control of AMPAR potentiation, AMPAR membrane trafficking and synaptic plasticity. Regulates AMPAR-mediated miniature excitatory postsynaptic currents. Exhibits dual GTPase-activating specificity for Ras and Rap. May be involved in certain forms of brain injury, leading to long-term learning and memory deficits. |
Protein Name | Ras/Rap Gtpase-Activating Protein SyngapNeuronal RasgapSynaptic Ras Gtpase-Activating Protein 1Synaptic Ras-Gap 1 |
Database Links | Reactome: R-HSA-5658442 |
Alternative Antibody Names | Anti-Ras/Rap Gtpase-Activating Protein Syngap antibodyAnti-Neuronal Rasgap antibodyAnti-Synaptic Ras Gtpase-Activating Protein 1 antibodyAnti-Synaptic Ras-Gap 1 antibodyAnti-SYNGAP1 antibodyAnti-KIAA1938 antibody |
Information sourced from Uniprot.org