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Anti-syndecan 1/CD138 antibody (Internal) (STJ73362)

Anti-syndecan 1/CD138 antibody (Internal) (STJ73362)

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STJ73362-100

£193.50

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Host:	Goat
Applications:	Pep-ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Goat polyclonal antibody anti-syndecan 1/CD138 (Internal) is suitable for use in ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	0.5 mg/mL
Dilution Range:	Peptide ELISA: antibody detection limit dilution 1:2000. WB: Approx 37kDa band observed in preliminary testinjg of HepG2, cell lysate after 1ug/ml of antibody staining (calculated MW of 32.5kDa according to NP_002988.3). Primary incubation 1 hour
Storage Instruction:	Store at-20°C on receipt and minimise freeze-thaw cycles.

Gene Symbol:	SDC1
Gene ID:	6382
Uniprot ID:	SDC1_HUMAN
Immunogen Region:	Internal
Accession Number:	NP_002988.3
Specificity:	Reported variants represent identical protein: NP_001006947.1, NP_002988.3.
Immunogen Sequence:	REQEATPRPRETTQ

Post Translational Modifications	Shedding is enhanced by a number of factors such as heparanase, thrombin or EGF. Also by stress and wound healing. PMA-mediated shedding is inhibited by TIMP3.
Function	Cell surface proteoglycan that contains both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP. Able to induce its own expression in dental mesenchymal cells and also in the neighboring dental epithelial cells via an MSX1-mediated pathway.
Protein Name	Syndecan-1 Synd1 Cd Antigen Cd138
Database Links	Reactome: R-HSA-1971475 Reactome: R-HSA-2022928 Reactome: R-HSA-2024096 Reactome: R-HSA-202733 Reactome: R-HSA-3000170 Reactome: R-HSA-3560783 Reactome: R-HSA-3560801 Reactome: R-HSA-3656237 Reactome: R-HSA-3656253 Reactome: R-HSA-4420332 Reactome: R-HSA-449836 Reactome: R-HSA-9694614 Reactome: R-HSA-975634 Reactome: R-HSA-9820960 Reactome: R-HSA-9833110
Cellular Localisation	Membrane Single-Pass Type I Membrane Protein Secreted Extracellular Exosome Shedding Of The Ectodomain Produces A Soluble Form
Alternative Antibody Names	Anti-Syndecan-1 antibody Anti-Synd1 antibody Anti-Cd Antigen Cd138 antibody Anti-SDC1 antibody Anti-SDC antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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