• Western blot analysis of SKOV3, BT474, Jurkat, PC-3, U937, MCF7 cells using SCP-2 Polyclonal Antibody.. Secondary antibody was diluted at 1:20000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003, Inventbiotech, MN, USA).

Anti-SYCP2 antibody (Internal) (STJ96481)

SKU:
STJ96481

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/ELISA/IHC
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Synaptonemal complex protein 2 (Internal) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
IHC-P 1:50-300
ELISA 2000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SYCP2
Gene ID: 10388
Uniprot ID: SYCP2_HUMAN
Immunogen Region: Internal
Specificity: SCP-2 Polyclonal Antibody detects endogenous levels of SCP-2 protein.
Immunogen: Synthesized peptide derived from the Internal region of human SCP-2.
Function Major component of the axial/lateral elements of synaptonemal complexes (SCS) during meiotic prophase. Plays a role in the assembly of synaptonemal complexes. Required for normal meiotic chromosome synapsis during oocyte and spermatocyte development and for normal male and female fertility. Required for insertion of SYCP3 into synaptonemal complexes. May be involved in the organization of chromatin by temporarily binding to DNA scaffold attachment regions. Requires SYCP3, but not SYCP1, in order to be incorporated into the axial/lateral elements.
Protein Name Synaptonemal Complex Protein 2
Scp-2
Synaptonemal Complex Lateral Element Protein
Hsscp2
Database Links Reactome: R-HSA-1221632
Cellular Localisation Nucleus
Chromosome
In Axial/Lateral Elements Of The Tripartite Segments Of Synaptonemal Complexes
Alternative Antibody Names Anti-Synaptonemal Complex Protein 2 antibody
Anti-Scp-2 antibody
Anti-Synaptonemal Complex Lateral Element Protein antibody
Anti-Hsscp2 antibody
Anti-SYCP2 antibody
Anti-SCP2 antibody

Information sourced from Uniprot.org

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