| Short Description : | Rabbit polyclonal anti-Synaptic vesicle glycoprotein 2B (1-50 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SV2B |
| Gene ID: | 9899 |
| Uniprot ID: | SV2B_HUMAN |
| Immunogen: | Synthesized peptide derived from part of the human protein.at the amino acid range 1-50 |
| Immunogen Region: | 1-50 aa |
| Specificity: | SV2B Polyclonal Antibody detects endogenous levels of protein. |
| Function | Probably plays a role in the control of regulated secretion in neural and endocrine cells. (Microbial infection) Receptor for the C.botulinum neurotoxin type A2 (BoNT/A, botA).glycosylation is not essential but enhances the interaction. Probably also serves as a receptor for the closely related C.botulinum neurotoxin type A1. |
| Protein Name | Synaptic Vesicle Glycoprotein 2b |
| Database Links | Reactome: R-HSA-5250955Reactome: R-HSA-5250968Reactome: R-HSA-5250981Reactome: R-HSA-5250992 |
| Cellular Localisation | Cytoplasmic VesicleSecretory VesicleSynaptic Vesicle MembraneMulti-Pass Membrane ProteinAcrosomeAssociated With Synaptic-Like Microvesicles But Not With Insulin-Containing Vesicles In Insulin-Secreting Cells Of The PancreasLocalizes To Microvesicles In The PinealocytesLocalizes To The Acrosome In Spermatids |
| Alternative Antibody Names | Anti-Synaptic Vesicle Glycoprotein 2b antibodyAnti-SV2B antibodyAnti-KIAA0735 antibody |
Information sourced from Uniprot.org
