| Short Description : | Mouse monoclonal Surfactant (241-336aa) antibody for use in IHC-P in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IHC-P |
| Host: | Mouse |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | ZM124 |
| Isotype: | IgG1k |
| Conjugation: | Unconjugated |
| Purification: | Affinity purified |
| Dilution Range: | 1:100-200 |
| Formulation: | Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin |
| Storage Instruction: | Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C. |
| Gene Symbol: | RNASE1 |
| Gene ID: | 6035 |
| Uniprot ID: | RNAS1_HUMAN |
| Immunogen: | Recombinant fragment (around aa 241-336) of human SFTPD protein |
| Immunogen Region: | 241-336aa |
| Specificity: | Positive control: Lung adenocarcinoma |
| Tissue Specificity | Pancreas and other tissues and body fluids (indicating it may have other physiological functions besides its role in digestion). |
| Post Translational Modifications | N-linked glycans are of complex type. |
| Function | Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single-stranded and double-stranded RNA. |
| Protein Name | Ribonuclease PancreaticHp-RnaseRib-1Rnase Upi-1Ribonuclease 1Rnase 1Ribonuclease ARnase A |
| Database Links | Reactome: R-HSA-9613829Reactome: R-HSA-9615710Reactome: R-HSA-9925561 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Ribonuclease Pancreatic antibodyAnti-Hp-Rnase antibodyAnti-Rib-1 antibodyAnti-Rnase Upi-1 antibodyAnti-Ribonuclease 1 antibodyAnti-Rnase 1 antibodyAnti-Ribonuclease A antibodyAnti-Rnase A antibodyAnti-RNASE1 antibodyAnti-RIB1 antibodyAnti-RNS1 antibody |
Information sourced from Uniprot.org
![Western blot analysis of lysates from wild type (WT) and GSTO1 knockout (KO) 293T cells, using [KO Validated] GSTO1 Rabbit polyclonal antibody (STJ11100768) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/89705/358188/STJ11100768_1__90554.1713122502.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and GSTO1 knockout (KO) 293T cells, using [KO Validated] GSTO1 Rabbit polyclonal antibody (STJ11100768) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.")
