| Host: | Rabbit |
| Applications: | WB/IHC-P |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit monoclonal anti-Superoxide Dismutase 3 for use in WB and IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | R08-4J3 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification: | Affinity Chromatography |
| Dilution Range: | WB 1:500-1:1000IHC 1:50-1:100 |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | SOD3 |
| Gene ID: | 6649 |
| Uniprot ID: | SODE_HUMAN |
| Immunogen: | A synthesized peptide derived from human Superoxide Dismutase 3 |
| Tissue Specificity | Expressed in blood vessels, heart, lung, kidney and placenta. Major SOD isoenzyme in extracellular fluids such as plasma, lymph and synovial fluid. |
| Function | Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen. |
| Protein Name | Extracellular Superoxide Dismutase Cu-ZnEc-Sod |
| Database Links | Reactome: R-HSA-3299685Reactome: R-HSA-9818027 |
| Cellular Localisation | SecretedExtracellular SpaceGolgi ApparatusTrans-Golgi Network99% Of Ec-Sod Is Anchored To Heparan Sulfate Proteoglycans In The Tissue InterstitiumAnd 1% Is Located In The Vasculature In Equilibrium Between The Plasma And The Endothelium |
| Alternative Antibody Names | Anti-Extracellular Superoxide Dismutase Cu-Zn antibodyAnti-Ec-Sod antibodyAnti-SOD3 antibody |
Information sourced from Uniprot.org