Anti-Superoxide dismutase 1 antibody (aa: 24-36) (STJA0040879)

Name: Anti-Superoxide dismutase 1 antibody (aa: 24-36) (STJA0040879)
SKU: STJA0040879-100
Price: 528.5 GBP
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeMixed

ImmunogenA synthetic peptide (ASGEPVV LSGQIT) as part of mouse superoxide dismutase (SOD1) protein (aa: 24-36) conjugated to diphtheria toxoid

STJA0040879-100

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Short Description	Rabbit polyclonal anti-Superoxide dismutase 1 (aa: 24-36) for use in WB in Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB
Host	Rabbit
Reactivity	Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	Mixed
Conjugation	Unconjugated
Purification	Whole serum
Dilution Range	WB 1:500-1:1000
Storage Instruction	Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. After reconstitution keep aliquots at-20°C for a higher stability, and at 2-8°C with an appropriate antibacterial

Gene Symbol	Sod1
Gene ID	20655
Uniprot ID	SODC_MOUSE
Immunogen	A synthetic peptide (ASGEPVV LSGQIT) as part of mouse superoxide dismutase (SOD1) protein (aa: 24-36) conjugated to diphtheria toxoid
Immunogen Region	aa: 24-36
Immunogen Sequence	Mouse
Specificity	Specificity was confirmed by Western blot detecting mouse superoxide dismutase (SOD1). This antiserum is known to react with mouse and rat superoxide dismutase (SOD1) protein.

Post Translational Modifications	Palmitoylation helps nuclear targeting and decreases catalytic activity. Succinylation, adjacent to copper catalytic site, probably inhibits activity. Desuccinylation by SIRT5 enhances activity.
Function	Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
Protein Name	Superoxide Dismutase Cu-Zn
Database Links	Reactome: R-MMU-114608 Reactome: -MMU-3299685
Cellular Localisation	Cytoplasm Nucleus
Alternative Antibody Names	Anti-Superoxide Dismutase Cu-Zn antibody Anti-Sod1 antibody

Information sourced from Uniprot.org