Function | Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of dopamine, small phenols such as 1-naphthol and p-nitrophenol and thyroid hormones, including 3,3'-diiodothyronine, triidothyronine (T3) and reverse triiodothyronine (rT3). May play a role in gut microbiota-host metabolic interaction. O-sulfonates 4-ethylphenol (4-EP), a dietary tyrosine-derived metabolite produced by gut bacteria. The product 4-EPS crosses the blood-brain barrier and may negatively regulate oligodendrocyte maturation and myelination, affecting the functional connectivity of different brain regions associated with the limbic system. |
Protein Name | Sulfotransferase 1b1St1b1Sulfotransferase 1b2Sulfotransferase Family Cytosolic 1b Member 1Thyroid Hormone Sulfotransferase |
Database Links | Reactome: R-HSA-156584 |
Cellular Localisation | Cytoplasm |
Alternative Antibody Names | Anti-Sulfotransferase 1b1 antibodyAnti-St1b1 antibodyAnti-Sulfotransferase 1b2 antibodyAnti-Sulfotransferase Family Cytosolic 1b Member 1 antibodyAnti-Thyroid Hormone Sulfotransferase antibodyAnti-SULT1B1 antibodyAnti-ST1B2 antibodyAnti-SULT1B2 antibody |
Information sourced from Uniprot.org