Anti-SUCLA2 antibody (STJA0006825)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human SUCLA2
General Information
| Short Description | Rabbit polyclonal anti-Succinate--CoA ligase subunit beta, mitochondrial for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SUCLA2 |
| Gene ID | 8803 |
| Uniprot ID | SUCB1_HUMAN |
| Immunogen | Synthesized peptide derived from human SUCLA2 |
| Specificity | This antibody detects endogenous levels of SUCLA2 at Human, Mouse |
Additional Info
| Function | ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. |
| Protein Name | Succinate--Coa Ligase Adp-Forming Subunit Beta - MitochondrialAtp-Specific Succinyl-Coa Synthetase Subunit BetaA-ScsSuccinyl-Coa Synthetase Beta-A ChainScs-Betaa |
| Database Links | Reactome: R-HSA-71403 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Succinate--Coa Ligase Adp-Forming Subunit Beta - Mitochondrial antibodyAnti-Atp-Specific Succinyl-Coa Synthetase Subunit Beta antibodyAnti-A-Scs antibodyAnti-Succinyl-Coa Synthetase Beta-A Chain antibodyAnti-Scs-Betaa antibodyAnti-SUCLA2 antibody |
Information sourced from Uniprot.org