Anti-SUCLA2 antibody (1-180) (STJ112080)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SUCLA2 (1-180) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SUCLA2 |
| Gene ID | 8803 |
| Uniprot ID | SUCB1_HUMAN |
| Immunogen Region | 1-180 |
| Immunogen Sequence | MAASMFYGRLVAVATLRNHR PRTAQRAAAQVLGSSGLFNN HGLQVQQQQQRNLSLHEYMS MELLQEAGVSVPKGYVAKSP DEAYAIAKKLGSKDVVIKAQ VLAGGRGKGTFESGLKGGVK IVFSPEEAKAVSSQMIGKKL FTKQTGEKGRICNQVLVCER KYPRREYYFAITMERSFQGP |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human SUCLA2 (NP_003841.1). |
Additional Info
| Tissue Specificity | Widely expressed. Not expressed in liver and lung. |
| Function | ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. |
| Protein Name | Succinate--Coa Ligase Adp-Forming Subunit Beta - MitochondrialAtp-Specific Succinyl-Coa Synthetase Subunit BetaA-ScsSuccinyl-Coa Synthetase Beta-A ChainScs-Betaa |
| Database Links | Reactome: R-HSA-71403 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Succinate--Coa Ligase Adp-Forming Subunit Beta - Mitochondrial antibodyAnti-Atp-Specific Succinyl-Coa Synthetase Subunit Beta antibodyAnti-A-Scs antibodyAnti-Succinyl-Coa Synthetase Beta-A Chain antibodyAnti-Scs-Betaa antibodyAnti-SUCLA2 antibody |
Information sourced from Uniprot.org