| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Syntaxin-17 (30-80 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
STX17 |
| Gene ID: |
55014 |
| Uniprot ID: |
STX17_HUMAN |
| Immunogen Region: |
30-80 aa |
| Specificity: |
This antibody detects endogenous levels of STX17 at Human/Mouse/Rat |
| Immunogen: |
Synthesized peptide derived from the human STX17 at the amino acid range 30-80 |
| Function | SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. STX17 is a SNARE of the autophagosome involved in autophagy through the direct control of autophagosome membrane fusion with the lysosome membrane. May also play a role in the early secretory pathway where it may maintain the architecture of the endoplasmic reticulum-Golgi intermediate compartment/ERGIC and Golgi and/or regulate transport between the endoplasmic reticulum, the ERGIC and the Golgi. |
| Protein Name | Syntaxin-17 |
| Database Links | Reactome: R-HSA-204005 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane ProteinSmooth Endoplasmic Reticulum MembraneEndoplasmic Reticulum-Golgi Intermediate Compartment MembraneCytoplasmic VesicleAutophagosome MembraneCopii-Coated Vesicle MembraneCytoplasmCytosolMitochondrion MembraneHas A Hairpin-Like Insertion Into MembranesLocalizes To The Completed Autophagosome Membrane Upon Cell Starvation |
| Alternative Antibody Names | Anti-Syntaxin-17 antibodyAnti-STX17 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
