| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | STX12 |
| Gene ID: | 23673 |
| Uniprot ID: | STX12_HUMAN |
| Immunogen Region: | 1-276 |
| Immunogen Sequence: | MSYGPLDMYRNPGPSGPQLR DFSSIIQTCSGNIQRISQAT AQIKNLMSQLGTKQDSSKLQ ENLQQLQHSTNQLAKETNEL LKELGSLPLPLSTSEQRQQR LQKERLMNDFSAALNNFQAV QRRVSEKEKESIARARAGSR LSAEERQREEQLVSFDSHEE WNQMQSQEDEVAITEQDLEL IKERETAIRQLEADILDVNQ IFKDLAMMIHDQGDLIDSIE ANVESSEVHVERATEQLQR |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-276 of human STX12 (NP_803173.1). |
| Function | SNARE promoting fusion of transport vesicles with target membranes. Together with SNARE STX6, promotes movement of vesicles from endosomes to the cell membrane, and may therefore function in the endocytic recycling pathway. Through complex formation with GRIP1, GRIA2 and NSG1 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting. |
| Protein Name | Syntaxin-12 |
| Database Links | |
| Cellular Localisation | Endosome MembraneSingle-Pass Type Iv Membrane ProteinGolgi Apparatus MembraneEndomembrane SystemCytoplasmic SideEarly Endosome MembraneRecycling Endosome Membrane |
| Alternative Antibody Names | Anti-Syntaxin-12 antibodyAnti-STX12 antibody |
Information sourced from Uniprot.org
