• Immunohistochemistry analysis of paraffin-embedded human liver damage using STRN antibody (STJ110045) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of paraffin-embedded rat heart using STRN antibody (STJ110045) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of paraffin-embedded mouse brain using STRN antibody (STJ110045) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Western blot analysis of extracts of various cell lines, using STRN antibody (STJ110045) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 30s.

Anti-STRN antibody (581-780) (STJ110045)

SKU:
STJ110045

£112.50 - £524.50
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Host: Rabbit
Applications: WB/IHC-P/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
IHC-P:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: STRN
Gene ID: 6801
Uniprot ID: STRN_HUMAN
Immunogen Region: 581-780
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 581-780 of human STRN (NP_003153.2).
Immunogen Sequence: HQRLLSCSADGTLRLWNTTE VAPALSVFNDTKELGIPASV DLVSSDPSHMVASFSKGYTS IFNMETQQRILTLESNVDTT ANSSCQINRVISHPTLPISI TAHEDRHIKFYDNNTGKLIH SMVAHLEAVTSLAVDPNGLY LMSGSHDCSIRLWNLESKTC IQEFTAHRKKFEESIHDVAF HPSKCYIASAGADALAKVFV
Tissue Specificity Preferentially expressed in brain.
Function Calmodulin-binding scaffolding protein which is the center of the striatin-interacting phosphatase and kinase (STRIPAK) complexes. STRIPAK complexes have critical roles in protein (de)phosphorylation and are regulators of multiple signaling pathways including Hippo, MAPK, nuclear receptor and cytoskeleton remodeling. Different types of STRIPAK complexes are involved in a variety of biological processes such as cell growth, differentiation, apoptosis, metabolism and immune regulation (Probable).
Protein Name Striatin
Database Links Reactome: R-HSA-1257604
Reactome: R-HSA-2219530
Reactome: R-HSA-6811558
Reactome: R-HSA-9009391
Reactome: R-HSA-9673766
Reactome: R-HSA-9700645
Reactome: R-HSA-9725370
Cellular Localisation Cytoplasm
Membrane
Peripheral Membrane Protein
Cell Projection
Dendritic Spine
Cttnbp2-Binding May Regulate Dendritic Spine Distribution
Alternative Antibody Names Anti-Striatin antibody
Anti-STRN antibody

Information sourced from Uniprot.org

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