| Post Translational Modifications | Phosphorylated. |
| Function | Meiosis-inducer required for the transition into meiosis for both female and male germ cells. In female germ cells, acts downstream of ZGLP1 as a key effector of the meiotic program: required for premeiotic DNA replication and subsequent events in meiotic prophase. During spermatogenesis, next to its role in meiotic initiation, promotes (but is not required for) spermatogonial differentiation. In complex with MEIOSIN, directly activates the transcription of a subset of critical meiotic genes playing a central role in cell-cycle switching from mitosis to meiosis. |
| Protein Name | Stimulated By Retinoic Acid Gene 8 Protein Homolog |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusShuttles Between Nucleus And CytoplasmNuclear Export Is Xpo1-Dependent |
| Alternative Antibody Names | Anti-Stimulated By Retinoic Acid Gene 8 Protein Homolog antibodyAnti-STRA8 antibody |
Information sourced from Uniprot.org