| Host: | Mouse |
| Applications: | ELISA/WB/ICC/IF |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal anti-STOM (55-288aa) for use in ELISA, WB, ICC and IF in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | AT33F5 |
| Conjugation: | Unconjugated |
| Isotype: | IgG2bk |
| Formulation: | Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Purification: | By protein-A affinity chromatography |
| Concentration: | 1 mg/mL |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | STOM |
| Gene ID: | 2040 |
| Uniprot ID: | STOM_HUMAN |
| Immunogen Region: | 55-288aa |
| Accession Number: | NP_004090 |
| Immunogen: | Recombinant human STOM (55-288aa) purified from E. coli |
| Tissue Specificity | Detected in erythrocytes (at protein level). Widely expressed. |
| Function | Regulates ion channel activity and transmembrane ion transport. Regulates ASIC2 and ASIC3 channel activity. |
| Protein Name | StomatinErythrocyte Band 7 Integral Membrane ProteinErythrocyte Membrane Protein Band 7.2Protein 7.2b |
| Database Links | Reactome: R-HSA-2672351Reactome: R-HSA-6798695Reactome: R-HSA-8980692Reactome: R-HSA-9013026Reactome: R-HSA-9013106Reactome: R-HSA-9013148Reactome: R-HSA-9013406Reactome: R-HSA-9013407Reactome: R-HSA-9013409 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinCytoplasmic SideCytoplasmCytoskeletonLipid-AnchorMembrane RaftMelanosomeCytoplasmic VesicleLocalizes To Juxtanuclear Structure Probably Derived From The Golgi ApparatusColocalizes With Cortical Actin Microfilaments At Small Plasma Membrane ProtrusionsAssociates With Alpha-Granular Lipid RaftsTranslocates From The Alpha-Granular Lipid Rafts To The Cell Membrane On Thrombin Activation And Selectively Enriched In Released MicrovesiclesIdentified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv |
| Alternative Antibody Names | Anti-Stomatin antibodyAnti-Erythrocyte Band 7 Integral Membrane Protein antibodyAnti-Erythrocyte Membrane Protein Band 7.2 antibodyAnti-Protein 7.2b antibodyAnti-STOM antibodyAnti-BND7 antibodyAnti-EPB72 antibody |
Information sourced from Uniprot.org
